Utility of consecutive repeat HIT ELISA testing for heparin-induced thrombocytopenia
نویسندگان
چکیده
منابع مشابه
Heparin-Induced Thrombocytopenia (HIT) Syndrome
Heparin has been available as a clinical treatment and prevention for thromboembolic disease for half a century. Known complications of heparin therapy include bleeding, allergic reactions, osteoporosis, and thrombocytopenia. Heparin-induced thrombocytopenia (HIT) is a common and potentially grave adverse effect of heparin treatment. HIT is unusual among drug-induced thrombocytopenias in that i...
متن کاملheparin- induced thrombocytopenia (hit): a case report of cabg patient
heparin- induced thrombocytopenia (hit) is an antibody mediated adverse effect of heparin therapy which is classified into two subtypes, hit i which is non-immune, spontaneously reversible thrombocytopenia and; hit ii which is an autoimmune-mediated adverse effect of heparin therapy. in this case report, we described a 65-year old male patient with hit ii after coronary artery bypass grafting. ...
متن کاملHeparin induced thrombocytopenia
Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...
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3535.18. Leroux D, Hezard N, Lebreton A, et al. Prospectiveevaluation of a rapid nanoparticle-based lateralflow immunoassay (Stic Expert® HIT) for the diag-nosis of heparin-induced thrombocytopenia. Br JHaematol 2014; 166: 774-782.19. Warkentin TE, Sheppard JI, Moore JC, et al. Quanti-tative interpretation of optical density measure-ments using PF4-dependent enzy...
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Heparin-induced thrombocytopenia (HIT) is a prothrombotic and potentially fatal iatrogenic disorder mediated by IgG antibodies that target multimolecular complexes of platelet factor 4 (PF4) and heparin (1). Although the first description of the disorder dates back more than 50 years (2), it was not until the 1990s that the target antigen in HIT was identified and the now widely used anti-PF4/h...
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ژورنال
عنوان ژورنال: American Journal of Hematology
سال: 2008
ISSN: 0361-8609,1096-8652
DOI: 10.1002/ajh.21074